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翻訳家・翻訳者を目指している人 トライアル 16回目
- 624 :名無しさん@英語勉強中:2015/09/09(水) 13:01:30.30 ID:N/NvVBQI.net
- 医学論文です。日本語に翻訳してください。よろしくお願いします。
The trials were generally small and of poor quality and in many cases the published reports were inadequate for our purpose.
Pooling of the studies was not attempted due to the lack of common outcome measures and endpoints and the unavailability of some primary data.
Although minocycline was shown to be an effective treatment for acne vulgaris, in only two studies was it found to be superior to other tetracyclines.
Both of these were conducted under open conditions and had serious methodological problems.
A third study showed it to be more effective than 2% fusidic acid, applied topically, against inflammatory lesions in mild to moderate acne.
Differences in the way adverse drug reactions were identified could have accounted for the wide variation between studies in numbers of events reported.
This meant that no overall evaluation could be made of incidence rates of adverse events associated with minocycline therapy.
No RCT evidence was found to support the benefits of minocycline in acne resistant to other therapies and the dose response has only been evaluated up to eight weeks of therapy.
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